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Frontiers in Biology
The investigation of the interplay between genes, proteins, metabolites and diseases plays a central role in molecular and cellular biology. Whole genome sequencing has made it possible to examine the behavior of all the genes in a genome by high-throughput experimental techniques and to pinpoint molecular interactions on a genome-wide scale, which form the backbone of systems biology. In particular, Bayesian network (BN) is a powerful tool for the ab-initial identification of causal anddoi:10.1007/s11515-010-0023-8 fatcat:iiepdm5eknc7njtlb2aarj7yj4