E‐Posters

2021 Colorectal Disease  
The aim of this study was to characterise stoma function, stoma-related bother and acceptance among patients operated for rectal cancer and to investigate if there were any preoperative personal factors with predictive impact on long-term stoma-related bother. Method: The QoLiRECT (Quality of Life in RECTal cancer) study is a prospective multicentre study of patients with newly rectal cancer. This was a subgroup analysis of patients operated with a permanent colostomy with a 2-year follow-up.
more » ... nalised regression models with shrinkage estimation were used to predict the 1-and 2-year stomarelated bother using baseline data. The predictive value and the importance of the included variables were evaluated using bootstrap resampling techniques. Results: Within the QoLiRECT cohort of 1248 patients, 472 patients had an elective abdominoperineal excision or Hartmann's procedure with the formation of a permanent colostomy. The response rate was 80% (379 included patients). Overall stoma acceptance was high and a majority of patients were not bothered by their stoma; 77% and 83% at 1 and 2 years, respectively. The subgroup of patients with stoma-related bother had a high prevalence of difficulties, especially fear of leakage, and a low stoma acceptance in daily life. Both clinical and personal factors were associated with stoma-related bother. The most important factors were quality of life and physical health, but the prediction accuracy was low. Conclusion: Stoma-related bother was associated with overall stoma dysfunction. As stoma-related bother is a multifactorial problem, it was not possible to predict which patients will experience stomarelated bother. With an increasing number of rectal cancer survivors with a permanent stoma and potential life-long functional impairments it is therefore of importance to prevent stoma-related symptoms and optimise stoma function to reduce bother and increase stoma acceptance.
doi:10.1111/codi.15852 fatcat:rjgzsacemfbzjhe2ycatd7bbmq