ESIPT blocked CHEF based differential dual sensor for Zn2+ and Al3+in a pseudo-aqueous medium with intracellular bio-imaging applications and computational studies

Rabiul Alam, Tarun Mistri, Rahul Bhowmick, Atul Katarkar, Keya Chaudhuri, Mahammad Ali
2016 RSC Advances  
A novel H3SAL-NH probe exhibits ESIPT from the phenolic OH group to the azomethine N atom in the excited state. This is blocked in the presence of Zn2+ and Al3+ giving turn on fluorescence which is useful for imaging in live HepG2 cells.
doi:10.1039/c5ra18424j fatcat:q7nqgufclrahfkvxi7vueaostq