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Inhibitory Effects of High Concentrations of Estrogen, Progesterone and Tamoxifen on Proliferation of HeLa in Culture
배양된 HeLa 세포에서 고농도의 에스트로겐, 프로게스테론 및 타목시펜의 세포증식 억제효과
2011
Journal of Life Science
배양된 HeLa 세포에서 고농도의 에스트로겐, 프로게스테론 및 타목시펜의 세포증식 억제효과
This study examined the effects of estrogen, progesterone and tamoxifen at different concentrations and treatment periods on proliferation of a human cervical carcinoma cell line, HeLa, in culture, based on MTT assay. Estrogen did not have an effect on the cellular proliferation in concentrations up to 1 μg/ml for treatment periods of between 2.5 and 6 days, but significantly inhibited proliferation at a higher concentration of 10 μg/ml in a progressive manner with increasing treatment periods.
doi:10.5352/jls.2011.21.12.1746
fatcat:kdaxuxquzffrtd2u4wzesd6nke