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GeneHub-GEPIS is a web application that performs digital expression analysis in human and mouse tissues based on an integrated gene database. Using aggregated expressed sequence tag (EST) library information and EST counts, the application calculates the normalized gene expression levels across a large panel of normal and tumor tissues, thus providing rapid expression profiling for a given gene. The backend GeneHub component of the application contains pre-defined gene structures derived fromdoi:10.1093/nar/gkm381 pmid:17545196 pmcid:PMC1933245 fatcat:znnyvz2ez5aopb7aurvwkojygq