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Clinical presentation, diagnosis, pathogenesis and treatment options for lymphocytic colitis (Review)
International Journal of Molecular Medicine
Lymphocytic colitis (LC) is characterized by chronic or relapsing non-bloody watery diarrhea and a macroscopically normal colon. However, histopathological examination of colonic biopsy samples reveals an increased intraepithelial infiltration of lymphocytes (≥20/100 enterocytes), and increased inflammatory cells within the lamina propria, but with a normal mucosal architecture. The reported prevalence of LC varies from 14.2 to 45 per 100,000 individuals, while its reported incidence is betweendoi:10.3892/ijmm.2013.1385 pmid:23695201 fatcat:bskehb77j5fhzpeizq4jcvfxai