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Signal Detection of Potentially Drug-Induced Liver Injury in Children Using Electronic Health Records
2020
Frontiers in Pediatrics
This study proposes a quantitative 2-stage procedure to detect potential drug-induced liver injury (DILI) signals in pediatric inpatients using an data warehouse of electronic health records (EHRs). Methods: Eight years of medical data from a constructed database were used. A two-stage procedure was adopted: (i) stage 1: the drugs suspected of inducing DILI were selected and (ii) stage 2: the associations between the drugs and DILI were identified in a retrospective cohort study. Results: 1,196
doi:10.3389/fped.2020.00171
pmid:32373564
pmcid:PMC7177017
fatcat:e4pqqzs7ubfyxjcrlqep27qdbu