Abbreviations: AE, adverse event; LED, light-emitting diode; ICD, informed consent document; OTC, over-the-Counter; BID, bis in die Material and methods Study design and participants The study was a single-arm, open-label, safety and efficacy study of dry and sensitive skincare formulation Primrose E Radiant Skin Serum in terms of reduction in skin dryness by improving skin Abstract Background: Dry skin is an uncomfortable condition marked by scaling, itching, and cracking. Objectives: To

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... te the safety and efficacy of Primrose E Radiant Skin Serum in subjects with moderate to severely dry skin and sensitive skin. Methods: The study was conducted on 24 healthy female subjects, aged≥30 to≤55 years. Each subject applied a test product on face BID for consecutive 45 days. Effect of test product was evaluated for facial skin hydration/moisture by Corneometer® CM 825, radiance/glow by Skin-Glossymeter GL 200, subjective evaluation. Subject perception about the product was also evaluated. Results: There was a statistically significant (p<0.001) increase observed in skin hydration through Corneometer evaluation on both cheeks on Day 1, Day 21, at 24 hours after Day 21 and Day 45, statistically significant (p<0.001) increase observed in glow by Skin-Glossymeter GL 200onboth cheeks on Day 1, t Day 21, at 24 hours after Day 21 and Day 45 and no apparent adverse event was observed. Conclusions: Primrose E Radiant Skin Serum is safe and efficacious in increasing the skin hydration/moisturisation level. It was important to test the skin hydrating and glossiness effects of Primrose E over 24 hours. This was done during Visits 2 (Day 21) and Visit 3 (at 24 hours from Day 21) of the study. The clinical results showed that Primrose E provides up to 24hours of continuous hydration/moisturisation and glow/ radiance protection. There is an increase in the skin's radiance and it gives off a beautiful glow for subjects with moderate to even a severe dry skin condition. Primrose E is suitable for people with sensitive dry skin and found to be safe and effective. Citation: Gajjar T, Patel N, Patel M, et al. Enhanced efficacy of radiant skin serum in subjects with moderate to severe, dry and sensitive skin.