Levothyroxine sodium injections as hospital pharmacy products were prepared from L-thyroxine sodium and Thyradin-S tablet. An ion-pairing reversed-phase high-performance liquid chromatography was used for the determination of levothyoxine sodium. The recovery rates of levothyroxine sodium injections using L-thyroxine sodium and dissolved by 0.1N NaOH were between 98.0 and 99.9%, but those of products using Thyradin-S tablet were betweeen 9.0 and 11.8%. Stability of levothyroxine sodium

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... products was investigated in terms of their appearance and change of the content in 180 days. As a result, significant change was observed in some conditions of preservations. Thus, levothyroxine sodium injection that was preserved at room temperature under UV light showed a low residual rate. However, it is considered that the levothyroxine sodium injections be useful if they are preserved in a dark, cold place.