Disease burden of urinary tract infections among type 2 diabetes mellitus patients in the U.S

Shengsheng Yu, Alex Z. Fu, Ying Qiu, Samuel S. Engel, Ravi Shankar, Kimberly G. Brodovicz, Swapnil Rajpathak, Larry Radican
2014 Journal of diabetes and its complications  
Aims: Type 2 diabetes is a reported risk factor for more frequent and severe urinary tract infections (UTI). We sought to quantify the annual healthcare cost burden of UTI in type 2 diabetic patients. Methods: Adult patients diagnosed with type 2 diabetes were identified in MarketScan administrative claims data. UTI occurrence and costs were assessed during a 1-year period. We examined UTI-related visit and antibiotic costs among patients diagnosed with UTI, comparing those with versus without
more » ... ith versus without a history of UTI in the previous year (prevalent vs. incident UTI cases). We estimated the total incremental cost of UTI by comparing all-cause healthcare costs in patients with versus without UTI, using propensity score-matched samples. Results: Within the year, 8.2% (6,014/73,151) of subjects had ≥ 1 UTI, of whom 33.8% had a history of UTI. UTI-related costs among prevalent versus incident cases were, respectively, $603 versus $447 (p = 0.033) for outpatient services, $1,607 versus $1,819 (p = NS) for hospitalizations, and $61 versus $35 (p b 0.0001) for antibiotics. UTI was associated with a total all-cause incremental cost of $7,045 (95% CI: 4,130, 13,051) per patient with UTI per year. Conclusions: UTI is common and may impose a substantial direct medical cost burden among patients with type 2 diabetes.
doi:10.1016/j.jdiacomp.2014.03.012 pmid:24929797 fatcat:lfj4otagxzaldclqhqkxn5sgze