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Periodontitis is inflammation of the supporting tissues of teeth resulting in gingival detachment and disintegration of alveolar bone. Aims and objectives: The main objective of the study is to analyze the relation of 1,25-dihyroxyvitammin D and its protein in periodontitis. Material and methods: This cross-sectional study was conducted in Demontmorency College of Dentistry, Lahore during November 2018 to March 2019. The data was collected from 100 patients of both genders. The data wasdoi:10.5281/zenodo.3250333 fatcat:73edl75wobczjbtzzgdcpzg7oa