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We examine the organizational impact on phylogenetic databases of the increasing sophistication in the need and use of phylogenetic data. A primary issue is the use of the unnormalized representation of phylogenies in Newick format as a primitive data type in existing phylogenetic databases. In particular, we identify and enumerate a list of potential applications of such databases and queries (use-cases) that biologists may wish to see integrated into a phylogenetic database management system.doi:10.1109/bibe.2003.1188940 dblp:conf/bibe/NakhlehMBPD03 fatcat:krakyprgzrd43ds5w4qjotkpqq