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Protective effect of HMG CoA reductase inhibitors against running wheel activity induced fatigue, anxiety like behavior, oxidative stress and mitochondrial dysfunction in mice
2012
Pharmacological Reports
Chronic fatigue stress (CFS) is an important health problem with unknown causes and unsatisfactory prevention strategies, often characterized by long-lasting and debilitating fatigue, myalgia, impairment of neuro-cognitive functions along with other common symptoms. The present study has been designed to explore the protective effect of statins against running wheel activity induced fatigue anxiety. Methods: Male albino Laca mice (20-30 g) were subjected to swim stress induced fatigue in a
doi:10.1016/s1734-1140(12)70930-1
pmid:23406743
fatcat:lbhnchvf4zcvxeztmqwyn7eeju