Patterning of somatosympathetic reflexes
American Journal of Physiology. Regulatory Integrative and Comparative Physiology
Kerman, I. A., and B. J. Yates. Patterning of somatosympathetic reflexes. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R716-R724, 1999.-In a previous study, we reported that vestibular nerve stimulation in the cat elicits a specific pattern of sympathetic nerve activation, such that responses are particularly large in the renal nerve. This patterning of vestibulosympathetic reflexes was the same in anesthetized and decerebrate preparations. In the present study, we report
... tudy, we report that inputs from skin and muscle also elicit a specific patterning of sympathetic outflow, which is distinct from that produced by vestibular stimulation. Renal, superior mesenteric, and lumbar colonic nerves respond most strongly to forelimb and hindlimb nerve stimulation (ϳ60% of maximal nerve activation), whereas external carotid and hypogastric nerves were least sensitive to these inputs (ϳ20% of maximal nerve activation). In contrast to vestibulosympathetic reflexes, the expression of responses to skin and muscle afferent activation differs in decerebrate and anesthetized animals. In baroreceptor-intact animals, somatosympathetic responses were strongly attenuated (to Ͻ20% of control in every nerve) by increasing blood pressure levels to Ͼ150 mmHg. These findings demonstrate that different types of somatic inputs elicit specific patterns of sympathetic nerve activation, presumably generated through distinct neural circuits. cutaneous input; muscle input; vestibular system; exercise; pain The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.