Chemical analysis methods: Measurements for assessing environmental exposures to children using small amounts of serum and urine: state-of-the-art

JEAN-MARIE D DIMANDJA, JAMES GRAINGER, DONALD G PATTERSON, WAYMAN E TURNER, LARRY L NEEDHAM
2000 Journal of Exposure Science and Environmental Epidemiology  
This paper addresses the recent advances in gas chromatographic ( GC )-based instrumentation for the analytical determination of environmental toxicants using small samples. One-dimensional GC / time-of-flight mass spectrometry ( TOFMS ) and comprehensive two-dimensional GC ( GCÂGC ) are shown to drastically improve sample component resolution, sensitivity and overall analytical throughput. A presentation of the concepts behind the new state-of-theart, and results highlighting the advantages of the emerging technologies are presented.
doi:10.1038/sj.jea.7500124 fatcat:4ywjnkyzyre6bfdo6oqbte7tly