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Retroviral gene therapy in Germany with a view on previous experience and future perspectives
2021
Gene Therapy
AbstractGene therapy can be used to restore cell function in monogenic disorders or to endow cells with new capabilities, such as improved killing of cancer cells, expression of suicide genes for controlled elimination of cell populations, or protection against chemotherapy or viral infection. While gene therapies were originally most often used to treat monogenic diseases and to improve hematopoietic stem cell transplantation outcome, the advent of genetically modified immune cell therapies,
doi:10.1038/s41434-021-00237-x
pmid:33753908
pmcid:PMC8455336
fatcat:pr3i6hgnsjck7lsuejfrcjmj5m