SERPINA1 Z allele is associated with cystic fibrosis liver disease

Pierre-Yves Boëlle, Dominique Debray, Loic Guillot, Harriet Corvol
2019 Genetics in Medicine  
The SERPINA1 Z allele is associated with cystic fibrosis (CF)-related liver disease (CFLD), a common manifestation in patients with CF. We estimated CFLD incidence based on the SERPINA1 genotype in 3328 CF patients with CFLD-phenotype information.
doi:10.1038/s41436-019-0449-6 pmid:30739910 fatcat:ratierfedrgodb2kqrzt3tozuy