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Corresponding author. Graphical abstract Various computational methods are employed to analyze the various non-synonymous single nucleotide polymorphisms (nsSNPs) in the AKR1C3 gene, that is shown with the protein based approaches along with suitable inhibitors. ga1 Abstract Objective The Aldo-keto reductase family consists of a number of enzymes which are essential to the catalysis of redox transformation and which are also involved in intermediate metabolism and detoxification. Severaldoi:10.1016/j.jksus.2021.101514 fatcat:mehnbo774vgbfdmhcdq2g6djsu