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Lateral motion of fluorescently labeled acetylcholine receptors in membranes of developing muscle fibers
1976
Proceedings of the National Academy of Sciences of the United States of America
We have made direct, quantitative measurements of the lateral motion and age-dependent distribution of acetylcholine receptors (AChR) on the surface of rat myotubes in primary culture. AChR were fluorescently marked with tetramethylrhodamine-labeled a-bungarotoxin and AChR lateral motion was measured by the fluoresence photobleaching recovery technique. We found two coexisting distinct classes of AChR: (i) mobile, uniformly distributed AChR that appear on all myotubes shortly after fusion from
doi:10.1073/pnas.73.12.4594
pmid:1070010
pmcid:PMC431558
fatcat:6jiwoawhwnamzphy4bgtd5hicy