We report a case of giant aspergillosis of the sphenoid sinus. The patient was a 67-year-old female who presented with a headache. CT and MRI showed an irregular shadow in the sphenoid sinus and partial bone destruction of the sinus wall. Histopathlogical examination of an intranasal biopsy specimen revealed aspergillus. Endoscopic intranasal sphenoidostomy was performed to drain the sinus and for observation. Histopathlogical examination of the fungus ball also showed aspergillus, which was

more »

... invasive to the submucosa tissue. The patient was successfully treated with surgical debridement of the involved sinus and nasal saline irrigation.