Fasted High-Intensity Interval and Moderate-Intensity Exercise Do Not Lead to Detrimental 24-Hour Blood Glucose Profiles

Sam N Scott, Matt Cocks, Rob C Andrews, Parth Narendran, Tejpal S Purewal, Daniel J Cuthbertson, Anton J M Wagenmakers, Sam O Shepherd
2018 Journal of Clinical Endocrinology and Metabolism  
OBJECTIVE -To compare the effect of a bout of high intensity interval training (HIT) and a bout of moderate-intensity continuous training (MICT) on glucose levels over a 24-hour period. RESEARCH DESIGN AND METHODS -Fourteen people with type 1 diabetes (duration of type 1 diabetes 8.2 ± 1.4 years), all on basal-bolus regimen, completed a randomised counterbalanced crossover study. Continuous glucose monitoring was used to assess glycaemic control following a single bout of HIT (6 x 1min
more » ... (6 x 1min intervals) and 30mins of moderate-intensity continuous training (MICT) on separate days, compared to a non-exercise control day (CON). Exercise was undertaken following an overnight fast with omission of short-acting insulin. Finger-prick blood glucose samples were recorded pre and post-exercise to assess the acute changes in glycaemia during HIT and MICT. RESULTS -There was no difference in the incidence of or % time spent in hypoglycaemia, hyperglycaemia or target range over the 24-hour and nocturnal period (24:00-06:00h) between CON, HIT and MICT (P>0.05). Blood glucose concentrations were not significantly (P=0.49) altered from pre to post-exercise with HIT (+0.39 ± 0.42 mmol/L) or MICT (-0.39 ± 0.66 mmol/L), with no difference between exercise modes (P=1.00). CONCLUSIONS -HIT or 30 minutes of MICT can be carried out after an overnight fast with no increased risk of hypoglycaemia or hyperglycaemia, and provided the starting glucose is between 7-14 mmol/L, no carbohydrate is needed for these exercises. As HIT is a time-efficient form of exercise, the efficacy and safety of longterm HIT should now be explored. ABREVIATIONS HIT -High intensity interval training MICT -Moderate intensity continuous training CON -Control day of no exercise CGMS -Continuous glucose monitor system CHO -Carbohydrate EXTOD -Exercising for type 1 diabetes
doi:10.1210/jc.2018-01308 pmid:30252054 fatcat:kqyww4nhdjcavabnnzsfdseigi