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High resolution spatial transcriptome analysis by photo-isolation chemistry
[article]
2020
bioRxiv
pre-print
In multicellular organisms, individual cells are characterized by their gene expression profiles and the spatial interactions among cells enable the elaboration of complex functions. Expression profiling in spatially defined regions is crucial to elucidate cell interactions and functions. Here, we established a transcriptome profiling method coupled with photo-isolation chemistry (PIC) that allows the determination of expression profiles specifically from photo-irradiated regions of whole
doi:10.1101/2020.03.20.000984
fatcat:t2topgzrsrfixbfas37phl7ore