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After the second war, Wilson who participated in development of the atomic bomb in Los Alamos studied peaceful use of atomic energy and proposed a property of proton beam that has potential to treat cancer. According to his proposal, the first patient was treated with proton beam therapy at the University of California Berkley in 1954. The first series of proton beam therapy for patients with esophageal cancer was reported from Japan in 1993. After that many proton facilities in Japan reporteddoi:10.35772/ghm.2020.01083 pmid:34250290 pmcid:PMC8239379 fatcat:2n375rknkjhonibwceyj3jmrcu