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Development of difference spectrophotometric method for the estimation of leflunomide in tablet dosage form
2012
Chemical Industry and Chemical Engineering Quarterly
A new simple, accurate, precise, highly sensitive and reproducible difference spectrophotometric method for the determination of leflunomide in bulk and pharmaceutical dosage form is described. The difference spectroscopic method is based on the principle that leflunomide exhibit two different forms; in acidic and basic medium which differs in their absorption spectra. The difference spectra were obtained by reading the absorbance of leflunomide in 0.1 N HCl in the reference cell and the
doi:10.2298/ciceq110804016l
fatcat:oqukahzyxfhw7fqj2qqyy4x6je