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Distinguishing Enzyme Structures from Non-enzymes Without Alignments
2003
Journal of Molecular Biology
The ability to predict protein function from structure is becoming increasingly important as the number of structures resolved is growing more rapidly than our capacity to study function. Current methods for predicting protein function are mostly reliant on identifying a similar protein of known function. For proteins that are highly dissimilar or are only similar to proteins also lacking functional annotations, these methods fail. Here, we show that protein function can be predicted as
doi:10.1016/s0022-2836(03)00628-4
pmid:12850146
fatcat:tvehprwyw5ccfivolhbvdaoro4