Addressing the pitfalls when designing intervention studies to discover and validate biomarkers of habitual dietary intake

A. J. Lloyd, N. D. Willis, T. Wilson, H. Zubair, E. Chambers, I. Garcia-Perez, L. Xie, K. Tailliart, M. Beckmann, J. C. Mathers, J. Draper
2019 Metabolomics  
Dietary exposure monitoring within populations is reliant on self-reported measures such as Food Frequency Questionnaires and diet diaries. These methods often contain inaccurate information due to participant misreporting, non-compliance and bias. Urinary metabolites derived from individual foods could provide additional objective indicators of dietary exposure. For biomarker approaches to have utility it is essential that they cover a wide-range of commonly consumed foods and the methodology works in a real-world environment.
doi:10.1007/s11306-019-1532-3 pmid:31049735 pmcid:PMC6497620 fatcat:zy7lkfhnirfipdmd576oz5qo54