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Profile of apoptotic proteins in oral squamous cell carcinoma: A cluster analysis of 171 cases
Applied Cancer Research
Oral squamous cell carcinoma (OSCC) is the eighth most prevalent cancer worldwide. In recent large-scale studies, by immunohistochemistry and cluster analysis, several markers were associated with patient survival in various tumors. The aim of this study was to analyze the expression profiles of 23 proteins that have been linked to the inhibition (Bcl-2, Bcl-x, Bcl-xL, Bcl-2-related protein A1, BAG-1, and survivin) and promotion (Bak, Bax, Bim/Bod, Bim-Long, Bad, Bid, PUMA, Apaf-1, caspase-2,doi:10.1186/s41241-016-0008-2 fatcat:d36hsn6d2bdrhlfbq6ubnljsfu