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1 Keynote address by Nobel Laureate Phillip A. Sharp the 21st century opened with a revolution in RNA biology

Phillip A. Sharp
2015 Journal of Biomolecular Structure and Dynamics  

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The discoveries of RNA interference and the evolutionary conservation of microRNAs at the turn of the century heralded a revolution in RNA Biology and the development of important innovations. Of particular note is the emerging understanding of the wide ranging roles of non-coding RNAs. Long non-coding RNAs regulate the expression of genes through both cis and trans mechanisms and provide organization to the nucleus. Small non-coding RNAs channel gene expression to specific states and suppress
more » ... ransposon elements. Excitingly, these insights and others are now being translated into new treatments for diseases and control of plant pathogens. 2 His Nobel Lecture and his speculative commentary on "What does the Future Hold"?
doi:10.1080/07391102.2015.1032624 fatcat:w7iil7k3ize77bjkthcyi52ohy
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Phillip A. Sharp. "1 Keynote address by Nobel Laureate Phillip A. Sharp the 21st century opened with a revolution in RNA biology." Journal of Biomolecular Structure and Dynamics 33.sup1 (2015) 1-1