1 Keynote address by Nobel Laureate Phillip A. Sharp the 21st century opened with a revolution in RNA biology

Phillip A. Sharp
2015 Journal of Biomolecular Structure and Dynamics  
The discoveries of RNA interference and the evolutionary conservation of microRNAs at the turn of the century heralded a revolution in RNA Biology and the development of important innovations. Of particular note is the emerging understanding of the wide ranging roles of non-coding RNAs. Long non-coding RNAs regulate the expression of genes through both cis and trans mechanisms and provide organization to the nucleus. Small non-coding RNAs channel gene expression to specific states and suppress
more » ... ransposon elements. Excitingly, these insights and others are now being translated into new treatments for diseases and control of plant pathogens. 2 His Nobel Lecture and his speculative commentary on "What does the Future Hold"?
doi:10.1080/07391102.2015.1032624 fatcat:w7iil7k3ize77bjkthcyi52ohy