Sequencing andde novoassembly reveals genomic variations associated with differential responses ofCandida albicansATCC 10231 towards fluconazole, pH and non-invasive growth [article]

Gajanan Zore, Archana Thakre, Rajendra Patil, Chaithra Pradip, Bipin Balan
2018 bioRxiv   pre-print
The whole genome sequencing generated 8.09 million paired-end reads, which were assembled into 2,262 scaffolds totaling 17,113,050 bp in length. We predict 7,654 coding regions and 7,647 genes and annotated the coding regions with gene ontology terms based on similarity to other annotated genomes. Genome comparisons revealed variations (including SNP and indels in genes involved in pH response, fluconazole resistance and invasive growth) compared toC. albicansSC5314 and WO1.
doi:10.1101/302943 fatcat:wpb7q7g7mrh2zcmof7imjrk5ha