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Overcoming bias and systematic errors in next generation sequencing data
2010
Genome Medicine
High-throughput sequencing involves the parallel sequen cing of millions of DNA fragments simultaneously. Abstract Considerable time and e ort has been spent in developing analysis and quality assessment methods to allow the use of microarrays in a clinical setting. As is the case for microarrays and other high-throughput technologies, data from new high-throughput sequencing technologies are subject to technological and biological biases and systematic errors that can impact downstream
doi:10.1186/gm208
pmid:21144010
pmcid:PMC3025429
fatcat:unvc2hplnnes7ej2hv3aao55bq