ESTIMATION OF THYMIC SIZE IN PRETERM AND TERM NEONATES BY ULTRASONOGRAPHY I N TERTIARY HEALTH CENTRE OF WESTERN MAHARASTRA
Journal of Evolution of Medical and Dental Sciences
To determine sonographically the thymic index of the neonates and present values for the thymic index for various gestational ages who are born by uncomplicated pregnancies between gestational ages of 28 to and 40 weeks and correlate thymic index with various parameters like gestational age, birth weight, birth length, sex of neonate and mode of delivery. SETTING: Neonatal intensive care unit, Department of pediatrics, Krishna Institute of Medical Sciences hospital and research centre Karad,
... ch centre Karad, Maharashtra India. METHODS: A prospective observational study was conducted. Eighty neonates were included of various gestational age between gestational age of 28 to 40 weeks and ultrasonography is performed on day five of post natal age by single radiologist. The neonates having antenatal, intranatal, postnatal complication and those having congenital malformations are exclude from the study. The size of thymus was measured by measuring transverse diameter, anterioposterior diameter and longitudinal diameter and thymic index is then calculated. RESULTS: Thymic index of various gestational age are calculated. The thymic index for gestational age group of 28 to 30 weeks is comparable to thymic index for gestational age 31 to 33 weeks (P>0. 001) while the thymic index for other gestational age groups statistically differ (P<. 001). Overall the mean thymic index is less when compared to north Indian population and western population. The mean thymic has highest positive correlation to birth weight (r=8428). CONCLUSION: This study presents normative data for the ultrasound measurements of thymus of neonates of various gestational age. Thus thymic index can be considered as one of the parameter to assess the gestational age. Measuring the thymic size by estimating the thymic index also help in predicting the gestational age but large number of prospective studies are required to establish the standard values of thymic index for particular gestational age. Over all mean thymic index in our study is less as compared to north Indian population and western studies probably because of low nutritional status of population of this region.