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Septins in kidney: A territory little explored
Septins are a conserved family of GTP-binding proteins that assemble into cytoskeletal filaments to function in a highly sophisticated and physiologically regulated manner. Originally septins were discovered in the budding yeast as membrane-associated filaments that affect cell polarity and cytokinesis. In the last decades, much progress has been made in understanding the biochemical properties and cell biological functions of septins. In line with this, mammalian septins have been shown to bedoi:10.1002/cm.21477 pmid:30004646 fatcat:lfvgagiskncrjfsrl7e34uy52e