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Pro-fibrillatory Effects of K[ATP] Channel Opener and the Action Potential Duration Restitution Kinetics in Isolated Swine Right Ventricle
2004
Korean Circulation Journal
and objectives:It remains to be defined how K[ATP] Channel Opener facilitates to induce ventricular arrhythmias. The purposes of this study are to assess the effects of K[ARP] Channel Opener, PCO400, on the action potential duration (APD) and APD restitution (APDR) kinetics, and their relationship with induction of ventricular tachycardia (VT)/fibrillation (VF), pro-fibrillatory effects. Materials and Methods:We recorded transmembrane potentials (TMPs) by microelectrode technique to explore the
doi:10.4070/kcj.2004.34.3.296
fatcat:fregqgvtvjbi7hful5rduvs2pi