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The Effect of Crocin and its Mechanism of Action on Chronic Pain Induced by Spinal Cord Contusion in a Rat Model
2013
Modares Journal of Medical Sciences: Pathobiology
unpublished
Objective: Various approaches have been offered for resolution of pain resulting from spinal cord injuries. One approach is the use of herbal and natural products. In the present research, as a preliminary study, we investigate the effect of crocin on chronic pain induced by contusion in the rat spinal cord (SCI). Methods: We randomly divided female Wistar rats into five groups. Groups I and II were contused at the L1 level and immediately treated with crocin (50 mg/kg). These groups were
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