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Role of Pregabalin in Management of Pruritus: A Literature Review
Journal of Pharmacy & Pharmaceutical Sciences
Pruritus can be one of the distressing symptoms of many dermatologic, systemic, neurologic or psychiatric disorders. In each case, the origin of itch is in the skin and/or the nervous system. Involvement of the nervous system causes neurogenic, psychogenic or neuropathic itch. Itch sensation is transferred to the central nervous system via unmyelinated C-type nerve fibers, and many mediators and receptors engage in the its induction and transmission. Also it has been demonstrated that there aredoi:10.18433/j35k6n pmid:28057164 fatcat:ixomwcq2ifdipdjxy4skjiap6u