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Fourier transform ion cyclotron resonance (FTICR) provides the highest resolving power of any commercially available mass spectrometer. This advantage is most significant for species of low mass-to-charge ratio (m/z), such as metabolites. Unfortunately, FTICR spectra contain a very large number of data points, most of which are noise. This is most pronounced at the low m/z end of spectra, where data point density is the highest but peak density low. We therefore developed a filter that offersdoi:10.1007/s11306-010-0202-2 pmid:20676216 pmcid:PMC2899016 fatcat:a5p56qxdrbf6diy6sqxxgtubyq