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Does white matter structure or hippocampal volume mediate associations between cortisol and cognitive ageing?
2015
Psychoneuroendocrinology
Elevated glucocorticoid (GC) levels putatively damage specific brain regions, which in turn may accelerate cognitive ageing. However, many studies are cross-sectional or have relatively short follow-up periods, making it difficult to relate GCs directly to changes in cognitive ability with increasing age. Moreover, studies combining endocrine, MRI and cognitive variables are scarce, measurement methods vary considerably, and formal tests of the underlying causal hypothesis
doi:10.1016/j.psyneuen.2015.08.005
pmid:26298692
pmcid:PMC4642652
fatcat:hckia6henjdpbjpuu3mddyjtdy