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Possible new ways in the pharmacological treatment of bipolar disorder and comorbid alcoholism
Neuropsychiatric Disease and Treatment
About half of all bipolar patients have an alcohol abuse problem at some point of their lifetime. However, only one randomized, controlled trial of pharmacotherapy (valproate) in this patient population was published as of 2006. Therefore, we reviewed clinical trials in this indication of the last four years (using mood stabilizers, atypical antipsychotics, and other drugs). Priority was given to randomized trials, comparing drugs with placebo or active comparator. Published studies were founddoi:10.2147/ndt.s6741 fatcat:zy2tzwslhnfbroqvs7gyndu7ra