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Biomarker approaches in major depressive disorder evaluated in the context of current hypotheses
Biomarkers in Medicine
Major depressive disorder is a heterogeneous disorder, mostly diagnosed on the basis of symptomatic criteria alone. It would be of great help when specific biomarkers for various subtypes and symptom clusters of depression become available to assist in diagnosis and subtyping of depression, and to enable monitoring and prognosis of treatment response. However, currently known biomarkers do not reach sufficient sensitivity and specificity, and often the relation to underlying pathophysiology isdoi:10.2217/bmm.14.114 pmid:25731213 fatcat:qxlrzrfo6new7lyh6iu46dkun4