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The aim of the present study is to develop and evaluate gastro-retentive floating beads and floating in situ gels of griseofulvin (GF) in order enhance the dissolution rate and the bioavailability of GF. Different formulae of GF floating beads and floating in situ gels were prepared using sodium alginate, hydroxypropylmethyl cellulose (HPMC), carbopol, xanthan gum and pectin as polymers. The prepared formulae were evaluated for their physiochemical properties including the drug encapsulationfatcat:vsd5gh3w2rahbdapeoozidgg7a