Unilateral Acute Exacerbation of Pulmonary Fibrosis in Association with Sjoegren's Syndrome

Toru TAKAHASHI, Mikiya SATOH, Hidetoshi SATOH
1996 Internal medicine (Tokyo. 1992)  
A 70-year-old female had an abnormal chest roentgenogram. Infiltrative shadows were recognized in the right lung, and an open lung biopsy (OLB) specimen revealed usual interstitial pneumonia (UIP). Xerostomia, keratoconjunctivitis sicca, and lymphocyte infiltration in salivary glands were consistent with Sjogren's syndrome; she was diagnosed as having pulmonary fibrosis in association with Sjogren's syndrome(SjS-IP). Acute exacerbation occurred and she was successfully treated with
more » ... d with corticosteroids. Unilateral exacerbation and UIP in SjS-IP are rare. OLB is useful for diagnosis and to select a pertinent therapy if lung involvement is unilateral in Sjogren's syndrome. (Internal Medicine 35: 811-814, 1996)
doi:10.2169/internalmedicine.35.811 fatcat:oodb2zi6dfdctl6lhjbd5odsga