This study was to evaluate the effectiveness of antibiotic prophylaxis in clean laparoscopic surgery for benign ovarian tumor. Method: 84 patients underwent clean laparoscopic surgery including cystectomy and salpingo-oophorectomy at Osaka Rosai hospital from Jan 2004 to Jun 2006, and were allocated to two groups. One group received cefazolin 1g single dose as prophylactic antibiotics just before the initiation of operation (42 patients) and another group did not received it (42 patients). We

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... vestigated the incidence of surgical site infection (SSI) between two groups prospectively based on CDC guideline. Result: Age, BMI, preoperative serum albumin level, preoperative hospital stay, and duration of operation, postoperative glucose level did not differ significantly between two groups. 9.5% (4 patients) of women in the antibiotics group and 11.6% (5 patients) of women in the control group diagnosed Superficial incisional SSI. The incidence of Deep incisional SSI was 0% in both groups and the incidence of Organ/Space SSI was 4.8% (2 patients) and 2.4% (1 patient) respectively. The