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Cell Chemical Biology
Graphical Abstract Highlights d A novel class of genetically encoded fluorescent Ca 2+ indicators is developed d The new sensors are suitable for imaging Ca 2+ in organelles with high Ca 2+ levels d They can be used to visualize Ca 2+ signals in the ER d ER-targeted Ca 2+ sensors are successfully used to monitor ER Ca 2+ signals in vivodoi:10.1016/j.chembiol.2016.05.010 pmid:27291400 fatcat:h2ozqwlle5frrfl33nh52zs55q