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Imaging Bacterial Colonization of the Zebrafish Gut with Selective Plane Illumination
2012
Biophysical Journal
reservoirs. To disseminate within and between these hosts, spirochetes must migrate through complex, polymeric environments such as the basement membrane of the tick midgut and the dermis of the mammal. To date, most research on the motility of B. burgdorferi has been done in media that do not resemble the tissue milieus that B. burgdorferi encounter in vivo. Here we show that the motility of Borrelia in gelatin matrices in vitro resembles the pathogen's movements in the chronically infected
doi:10.1016/j.bpj.2011.11.833
fatcat:zk3tu7esaffjzn7agnjo3fnb2e