Role of Inflammatory Markers in Patients with Coronary Artery Ectasia versus Patients with Obstructive Coronary Artery Disease

Mohamed Abdel-shafy Tabl, Heba Abdel-kader Mansour, Eman Said El-keshk, Hani Asaad Kaddah
2018 Cardiology research and cardiovascular medicine  
Objective: The aim of the study is to compare between Eosinophilic Count (EC), Mean Platelet Volume, (MPV), Neutrophil/ Lymphocyte Ratio (NLR) and High Sensitive CRP (HS-CRP) level in patients with coronary artery ectasia versus patients with obstructive coronary artery disease. Methods: 150 patients underwent diagnostic coronary angiography in cardiology departments of Mahalla cardiology center and Benha University hospitals, divided into three groups, 50 patients with Coronary Artery Ectasia
more » ... ary Artery Ectasia (CAE), 50 patients with Obstructive Coronary Artery Disease (O-CAD) and 50 patients as a control group. Results: All parameters were found to be significantly increased when comparing patients have CAE or O-CAD with the controls (P<0.001). Plasma levels of EC and HS-CRP were significantly higher in CAE patients compared with O-CAD patients (0.202 ± 0.075, 0.126 ± 0.031/nl, P<0.001), (2.45 ± 0.5, 2.23 ± 0.42 mg/l, P=0.045) respectively. Meanwhile levels of MPV and NLR were insignificant in CAE patients compared to O-CAD patients (7.354 ± 0.623, 7.338 ± 0.486 mL, P=0.642),(2.857± 0.88, 2.667 ± 0.569, P=0.222) respectively. Conclusion: This study has revealed a relationship between plasma EC and HS-CRP and Coronary Artery Ectasia (CAE) in comparison to patients with Obstructive Coronary Artery Disease (O-CAD). These results confirm that CAE is a more severe inflammatory process than O-CAD.
doi:10.29011/2575-7083.000040 fatcat:blclohvyajftbgyagrqz34vwwu