Zebrafish Information Network, the knowledgebase for Danio rerio research

Yvonne M Bradford, Ceri E Van Slyke, Leyla Ruzicka, Amy Singer, Anne Eagle, David Fashena, Douglas G Howe, Ken Frazer, Ryan Martin, Holly Paddock, Christian Pich, Sridhar Ramachandran (+1 others)
2022 Genetics  
The Zebrafish Information Network (ZFIN, zfin.org) is the central repository for Danio rerio genetic and genomic data. ZFIN has served the zebrafish research community since 1994, expertly curating, integrating, and displaying zebrafish data. Key data types available at ZFIN include, but are not limited to, genes, alleles, human disease models, gene expression, phenotype, and gene function. ZFIN makes zebrafish research data Findable, Accessible, Interoperable, and Reusable through
more » ... curatorial and annotation activities, web interfaces, and data downloads. Recently, ZFIN and six other model organism knowledgebases have collaborated to form the Alliance of Genome Resources, aiming to develop sustainable genome information resources that enable the use of model organisms to understand the genetic and genomic basis of human biology and disease. Here we provide an overview of the data available at ZFIN including recent updates to the gene page to provide access to single-cell RNA sequencing (scRNA-seq) data, links to Alliance web pages, ribbon diagrams to summarize the biological systems and Gene Ontology terms that have annotations, and data integration with the Alliance of Genome Resources.
doi:10.1093/genetics/iyac016 pmid:35166825 pmcid:PMC8982015 fatcat:v737talhbvbqdn4edyablydogi