A Convenient Two-Step Synthesis of Coenzyme Q1 [post]

Yi-Yu Yan, Wan-Yue Luo, Yan Zhao, Jian-Hua Tian, Jin Wang
2019 unpublished
<p>A convenient method for the preparation of Coenzyme Q<sub>1</sub> from the cheap and readily available 3,4,5-Trimethoxytoluene was developed. CoQ<sub>1 </sub>was synthesized in moderate yield by a two-step procedure involving the key reaction of allyl bromide with CoQ<sub>0 </sub>through a redox chain reaction. The reaction is efficient and could be used for the synthesis of other CoQ compounds.</p>
doi:10.26434/chemrxiv.8115932.v1 fatcat:4dueue4x5zd6tj4tk6okqom6lm