cmvdrg - An R package for Human Cytomegalovirus antiviral Drug Resistance Genotyping [article]

Oscar J Charles, Cristina Venturini, Judith Breuer
2020 bioRxiv   pre-print
The prevention and treatment of HCMV infection is based on the utilization of antiviral therapies as HCMV lacks an effective vaccine. The rise of drug resistance is therefore an increasing patient threat. We identified the need for an open source and comprehensive HCMV resistance mutations database, to support the research community in this area. Here we present Cytomegalovirus Drug Resistance Genotyping (cmvdrg), a freely available database contained within an easily accessible R package,
more » ... provides a succinct extraction of literature material in the form of a text file database. Additionally, cmvdrg includes methods for calling resistance in common sequencing files and an optional user-friendly web interface.
doi:10.1101/2020.05.15.097907 fatcat:kqu6pjfs65a5bigzb4r2bnochi