Abbreviations 20-HETE -20-hydroxyeicosatetraenoic acid 5-BDBD -5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one α1 -adrenergic receptor type 1 AA -archidonic acid AFM -atomic force microscopy ARC -actin rich center ASIC -acid sensing ion channels AT 1A -angiotensin II receptor type 1A AT 1B -angiotensin II receptor type 1B AT 1 R-angiotensin II receptor type 1 ATP -adenosine 5'-triphosphate C--carboxyl-C. elegans -Caenorhabditis elegans cAMP -adenosine 3-,5-cyclic

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... te Ca V -voltage-gated calcium channel CDH23 -cadherin 23 CHO -chinese hamster ovary cm -centimeter COS -CV-1 in Origin with SV40 genes CysLT 1 R -cysteinyl leukotriene 1 receptor DA5 -distal arthrogryposis Type 5 DAG -diacylglycerol Deg/ENaC -Degenerin/Epithelial channel Na + channel DNA -2' deoxyribonucleic acid DRG -dorsal root ganglia EC -endothelial cell ECM -extracellular matrix EET -5',6'-epoxyeicosatrienoic acid ER -endoplasmic reticulum ET A -endothelin receptor type A ET B -endothelin receptor type B F -force FRET -Förster resonance energy transfer GTP -guanosine 5'-triphosphate GTPγS -guanosine 5'-O-[gamma-thio]triphosphate GPCR -G protein-coupled receptor Publications 7 Publications This dissertation contains results that are presented in the following publications: Storch U, Forst AL, Philipp M, Gudermann T, Mederos y Schnitzler M. Transient receptor potential channel 1 (TRPC1) reduces calcium permeability in heteromeric channel complexes.