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Clinical Significance of Galactose-Deficient IgA1 by KM55 in Patients with IgA Nephropathy
2019
Kidney & Blood Pressure Research
Aberrant galactose-deficient IgA1 molecules (Gd-IgA1) are important causal factors in IgA nephropathy (IgAN); however, the detection of Gd-IgA1 in IgAN is complicated and instable. A monoclonal antibody, KM55, which specifically recognizes Gd-IgA1 has been developed. In the present study, we further explored the clinical significance of Gd-IgA1 using KM55. In this study, we enrolled 75 patients with IgAN and 80 healthy controls and detected the plasma Gd-IgA1 levels using the KM55 ELISA method.
doi:10.1159/000502579
pmid:31574506
fatcat:24uwxh6fk5gddhgtnblqnxa3ta